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Sacituzumab govitecan shows promise in treating the most aggressive type of breast cancer

A unique antibody drug conjugate (ADC), which delivers a high dose of a cancer-killing drug to tumor cells through a targeted antibody, has been found in a global phase 3 clinical study to nearly double the survival time of patients with refractory metastatic triple-negative breast cancer. The study of the ADC drug sacituzumab govitecan (SG), […]

Dolutegravir is a first-line treatment for newly diagnosed HIV patients

A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV — an update that could affect nearly two million people per year worldwide. The study found that dolutegravir is the optimal medication for first-line treatment for people newly diagnosed with HIV, a choice that has not […]

mRNA Vaccine: For Illnesses From AIDS To Cancer

The coronavirus pandemic has made vaccines from Pfizer/BioNTech and Moderna and the mRNA technology that they use into household names. These types of jabs are new but researchers have been working for decades to try to figure out how to use messenger RNA for other vaccinations and to treat illnesses from AIDS to cancer. How […]

The Relationship Between The Diagnosis of Diabetes And The Use of Antidepressants And Antipsychotics

Almost three in ten people with type 2 diabetes (T2D) in Scotland were prescribed antidepressants before they were diagnosed with diabetes, according to new research being presented at the European Association for the Study of Diabetes (EASD) conference, held online this year. The study, from Ms Charlotte Greene, Professor Sarah Wild and colleagues at the […]

ADC Has Curative Effect On Cell Surface Protein In Neuroblastoma

Physician-scientists in the Cancer Center at Children’s Hospital of Philadelphia (CHOP) have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells. The researchers published their findings today in Science Translational Medicine. In 2008, researchers discovered mutations in the anaplastic lymphoma kinase (ALK) gene […]

Vitamin D May Prevent Severe COVID-19 Disease And Death

New research from Trinity College and University of Edinburgh has examined the association between vitamin D and COVID-19, and found that ambient ultraviolet B (UVB) radiation (which is key for vitamin D production in the skin) at an individual’s place of residence in the weeks before COVID-19 infection, was strongly protective against severe disease and […]

FDA Approved Increased Doses of The Vaccine For Certain Immunocompromised Individuals

On Aug 12, the U.S. Food and Drug Administration amended the emergency use authorizations (EUAs) for both the Pfizer-BioNTech COVID-19 Vaccine and the Moderna COVID-19 Vaccine to allow for the use of an additional dose in certain immunocompromised individuals, specifically, solid organ transplant recipients or those who are diagnosed with conditions that are considered to […]

How Do Immune Cells Defeat Cancer

The body’s immune system can recognize and attack cancer cells, but when those are able to overcome this assault, malignant tumors develop in patients. New research led by investigators at Massachusetts General Hospital (MGH) uncovers some of the key factors that are needed for survival of immune cells in the battle against cancer. The findings, […]

Existing Drugs May Inhibit SARS-CoV-2 Virus

The COVID-19 pandemic has caused more than 600,000 deaths in the United States since the start of 2020 and more than 4 million globally. The search for effective treatments against the disease are ongoing, and one hurdle is that SARS-CoV-2, the virus that causes COVID-19, has a number of tricks up its molecular sleeve when […]

What Factors Are Affecting The Effect of Cancer Treatment?

With social development and medical advances, people are living longer, but with that, many diseases are becoming more common, such as cancer. In 2020, there will be 19.3 million new cases of cancer and nearly 10 million deaths worldwide; and by 2040, the number of new cases is expected to reach 28.4 million, an increase […]