Protein A Resin Market to Grow at 11.4% CAGR to Hit $1.9 Billion by 2025

The growth in this Protein A Resin market is mainly driven by the growing demand for disposable pre-packed columns, increasing demand for therapeutic antibodies, and the increasing pharmaceutical R&D spending are expected to drive the growth of this market during the forecast period.

The protein A resin market is expected to reach USD 1.9 billion by 2025 from USD 1.1 billion in 2020, at a CAGR of 11.4% during the forecast period.

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Protein A Resin Market Dynamics

Drivers: Increasing demand for therapeutic antibodies

Chromatography is an essential step in the purification of monoclonal antibodies (mAbs). Over the past decade, there has been a tremendous increase in the demand for monoclonal antibodies in oncology and several other therapeutic areas, including neurological, autoimmune, and inflammatory disorders. As a result, almost all major pharmaceutical companies are focusing on the R&D of therapeutic antibodies.

Restrains: High cost of resins

Protein A resins cost around 5-10 times more than other types of resins. Though there are no alternative techniques that can achieve purification levels as high as protein A resins, their high cost makes end users look for alternatives. Some of the techniques that provide acceptable levels of purification include both chromatography and non-chromatography methods. mAb crystallization and precipitation by polyethylene glycol (PEG) precipitation are being explored as alternatives for protein A chromatography.

Opportunities: Increasing number of CMOs and CROs

Pharmaceutical companies are increasingly relying on contract manufacturers in various areas of research to fulfill a number of basic needs, such as specialized competencies and cost reduction. The pharmaceutical contract manufacturing industry has experienced robust growth in recent years, and this trend is expected to continue in the coming years. The increasing pressure from several governments to reduce healthcare costs and declining R&D productivity have compelled core pharmaceutical producers to rely on contract manufacturing. Moreover, the rising demand for generic drugs in China and India is a key driver for CMO sales.

North America to dominate the market in 2020

North America, Europe, Asia Pacific, and the Rest of the World (RoW) are the regions considered for geographic analysis of the global protein A resin market study. North America is expected to account for the largest share of the global protein A resin market. The large share of North America is attributed to the A strong monoclonal antibody therapeutics market in North America is the key driver for the protein A resin market in the region.

The prominent players in the global protein A resin market include GE Healthcare (US), Merck Millipore (Germany), Repligen Corporation (US), Thermo Fisher Scientific (US), Tosoh Bioscience (Japan), Purolite Corporation (US), Novasep Holding SAS (France), Agilent Technologies (US), GenScript Biotech Corporation (China), PerkinElmer (US), Bio-Rad Laboratories (US), Orochem (US), Kaneka Corporation (Japan), Abcam (UK), Agarose Bead Technologies (US), Avantor (US), JSR Life Sciences (US), Bio-Works Technologies (Sweden), Amikozen Co. Ltd. (US), and Takara Bio Inc. (Japan).

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